Publications by authors named "J P Fillon"
Article Synopsis
- The decreasing cost of sequencing and advancements in genomics technologies are increasing the demand for validated bioinformatics software for large-scale data processing.
- GenPipes is a Python-based framework designed for developing and deploying complex workflows, optimized for high-performance computing and the cloud.
- It offers 12 validated pipelines for various genomics applications, is open source, and allows researchers to easily analyze and customize their workflows based on their specific needs.
Introduction: The active clinical research programme of trabectedin continues to improve knowledge on the therapeutic activity and toxicity of the drug in the treatment of soft tissue sarcomas (STS). In contrast, limited number of data is available on its use outside of clinical trials.
Patients And Methods: We retrospectively analysed efficacy and safety of trabectedin when given in daily practice to patients with advanced/recurrent STS.
Background: Crizotinib, an oral tyrosine kinase inhibitor that targets anaplastic lymphoma kinase, has proven to offer sustained progression-free survival in anaplastic lymphoma kinase-rearranged non-small-cell lung cancers. Occurrence of severe interstitial lung disease (ILD) was one of the crucial adverse events reported in randomized clinical trials and case reports.
Methods: In September 2011, we observed a crizotinib-associated ILD case.
Introduction: Pemetrexed is approved to treat non-small cell lung cancer and has an overall favorable toxicity profile. A case of pemetrexed-induced cutaneous adverse events (CAE), i.e.
View Article and Find Full Text PDFThe Macromolecular Structure Database (MSD) (http://www.ebi.ac.
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