Publications by authors named "J P Duverger"

Induction-based breathing sensors in automobiles enable unobtrusive respiratory rate monitoring as an indicator of a driver's alertness and health. This paper introduces a quantitative method based on signal quality to guide the integration of textile inductive electrodes in automotive applications. A case study with a simplified setup illustrated the ability of the method to successfully provide basic design rules about where and how to integrate the electrodes on seat belts and seat backs to gather good quality respiratory signals in an automobile.

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Cell culture of cardiac tissue analog is becoming increasingly interesting for regenerative medicine (cell therapy and tissue engineering) and is widely used for high throughput cardiotoxicity. As a cost-effective approach to rapidly discard new compounds with high toxicity risks, cardiotoxicity evaluation is firstly done requiring cells/tissue with physiological/pathological characteristics (close to properties). Studying multicellular electrophysiological and contractile properties is needed to assess drug effects.

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The biological pacemaker approach is an alternative to cardiac electronic pacemakers. Its main objective is to create pacemaking activity from added or modified distribution of spontaneous cells in the myocardium. This paper aims to assess how automaticity strength of pacemaker cells (i.

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In native conditions, cardiac cells must continuously comply with diverse stimuli necessitating a perpetual adaptation. Polydimethylsiloxane (PDMS) is commonly used in cell culture to study cellular response to changes in the mechanical environment. The aim of this study was to evaluate the impact of using PDMS substrates on the properties of spontaneous activity of cardiomyocyte monolayer cultures.

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Article Synopsis
  • This study looked at how autoantibodies against a heart channel called KCNQ1 can affect the heart's electrical activity in rabbits.
  • The rabbits were given a vaccine to produce these autoantibodies, and it was found that their heart rhythms got faster and they were more likely to have irregular heartbeats.
  • The research suggests that this autoimmunity might help prevent some heart problems, like long QT syndrome, when treated with a specific drug.
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