Clinical interest of bone texture analysis in osteoporosis: a case control multicenter study.

Unlabelled: We demonstrate the clinical interest of bone texture analysis with a new high resolution X-ray device. We have found that the combination of BMD and texture parameter values provided a better assessment of the fracture risk than that obtainable solely by BMD measurement.

Introduction: Osteoporosis is characterized by BMD and trabecular bone microarchitecture.

Bone texture analysis on direct digital radiographic images: precision study and relationship with bone mineral density at the os calcis.

Assessment of bone microarchitecture in complement to bone mineral density (BMD) exam could improve prediction of osteoporotic fractures. A high-resolution X-ray prototype was developed to assess microarchitecture quality. Images were obtained on os calcis; then, three texture parameters were calculated on the same region of interest (ROI): a fractal parameter, a run-length parameter, and a co-occurrence parameter.