Publications by authors named "J P Daures"

Introduction: Incisional and parastomal hernias are frequent complications after cystectomy. The aim of our study was to define their incidence, identify risk factors related to the patient and the surgical technique, and identify means of prevention.

Material: This was a multicenter, retrospective study, analyzing clinical and radiological data from 521 patients operated on for cystectomy between January 2010 and December 2020.

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Hematological malignancies (HMs) have heterogeneous serological responses after vaccination due to disease or treatment. The aim of this real-world study was to analyze it after Pfizer-BioNT162b2 mRNA vaccination in 216 patients followed up for 1 year. The first 43 patients had an initial follow-up by a telemedicine (TM) system with no major events reported.

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  • PARP inhibitors can help breast cancer patients with BRCA1 or BRCA2 gene mutations, affecting their chances of survival during treatment, necessitating a reassessment of who should be tested for these mutations.
  • The study analyzed the occurrence of these mutations in breast cancer patients and unaffected individuals, revealing significant rates of gene carriage in both groups.
  • Findings showed that about 1.66% of breast cancer patients had gBRCA1, while 1.71% had gBRCA2, with a higher mutation frequency in ER- tumors compared to ER+ tumors.
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Objective: Multimorbidity is frequent in rheumatoid arthritis (RA) and could interfere with the therapeutic response. The aim of this study was to evaluate multimorbidity in the French cohort of early arthritis, the ESPOIR cohort, and its possible impact on the therapeutic response.

Methods: We included patients fulfilling 2010 ACR/EULAR criteria for RA.

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  • - A study in the French Hérault region examined breast cancer risk in over 10 million women at average risk, highlighting the need for a new predictive model tailored to the French population.
  • - Researchers followed 2,741 women aged 50 to 60 over 12 years, identifying key risk factors like high breast density and maternal history of breast cancer, alongside protective factors like early menopause.
  • - The study categorized women into three risk groups (lower, average, higher), proposing personalized screening strategies: reducing mammogram frequency for lower-risk women and increasing surveillance for higher-risk women, potentially affecting 600,000 women in the screening program.
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