Steroids and steroid-like compounds alter the ion permeability of phospholipid bilayers distinct interactions with lipids and interfacial water.

Steroids are organic compounds found in all forms of biological life. Besides their structural roles in cell membranes, steroids act as signalling molecules in various physiological processes and are used to treat inflammatory conditions. It has been hypothesised that in addition to their well-characterised genomic and non-genomic pathways, steroids exert their biological or pharmacological activities an indirect, nonreceptor-mediated membrane mechanism caused by steroid-induced changes to the physicochemical properties of cell membranes.

COVID-19 Misperceptions and Masking Compliance: A Support Marshaling Analysis.

Misperceptions strongly influence the extent to which individuals comply with preventative measures. Social support from others, particularly given widespread mistrust in news media among those holding misperceptions, plays an important role in shaping compliance with preventative measures. The impact of social support, however, is not straightforward and not all support results in greater compliance.

How Does the Pre-Registration Midwifery Programme Prepare the Newly Qualified Midwives for Their Post-Registration Perinatal Mental Health Role? A Mixed Methods Study.

Objective: In the United Kingdom (UK) and most countries worldwide, midwives are professionally required to undertake an initial perinatal mental health (PMH) risk assessment at every maternity contact. However, studies have found that midwives feel that they are not well-equipped to provide effective care for women with PMH needs. This study explores how the newly qualified midwives (NQMs) are prepared through pre-registration midwifery education and placements to have sufficient confidence in their , , , (KASH) for their post-registration PMH role.

Exploring sustainability in dairy cattle breeding focusing on feed efficiency and methane emissions.

Reducing emissions is vital to improve sustainability, and industry leaders have set emission goals to reduce gross emissions, lower emissions intensity, or reach net zero. However, additional traits should also be measured and compared in terms of their impact on the broader definition of sustainability. In addition to environmental impact, a sustainable breeding objective must consider profit, animal welfare, farmer well-being, and social responsibility.

Isoprene nitrates drive new particle formation in Amazon's upper troposphere.

New particle formation (NPF) in the tropical upper troposphere is a globally important source of atmospheric aerosols. It is known to occur over the Amazon basin, but the nucleation mechanism and chemical precursors have yet to be identified. Here we present comprehensive in situ aircraft measurements showing that extremely low-volatile oxidation products of isoprene, particularly certain organonitrates, drive NPF in the Amazonian upper troposphere.