Publications by authors named "J P Copeland"

Article Synopsis
  • Wolverines in North America have seen a reduction in their distribution due to human activities during the 19th and 20th centuries, leading to their threatened status in the US and special concern status in Canada.
  • A study collected 882 genetic samples to analyze landscape connectivity factors, focusing on terrain complexity, human disturbance, forest configuration, and climate across a vast region of southwestern Canada and northwestern US.
  • Findings showed that human disturbance negatively affects wolverine genetic connectivity, while forest cover and snow persistence help maintain genetic diversity, which can inform future conservation management efforts.
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Article Synopsis
  • - Mother's milk has diverse bacterial communities, and this study investigates how these bacteria affect the gut microbiota of very-low-birth-weight (VLBW) infants during hospitalization, analyzing 94 mother-infant pairs and 422 milk-stool samples.
  • - Approximately 30%-40% of the bacterial types found in the infants' guts are also present in the mother's milk, showing a direct link between milk consumption and gut microbiota development in VLBW infants, influenced by feeding practices and antibiotic use.
  • - The findings suggest that the microbiota in mother's milk plays a significant role in shaping the gut bacteria of VLBW infants, indicating that specific milk bacteria and their interactions are important for gut colonization.
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Formin Homology Proteins (Formins) are a highly conserved family of cytoskeletal regulatory proteins that participate in a diverse range of cellular processes. FMNL2 is a member of the Diaphanous-Related Formin sub-group, and previous reports suggest FMNL2's role in filopodia assembly, force generation at lamellipodia, subcellular trafficking, cell-cell junction assembly, and focal adhesion formation. How FMNL2 is recruited to these sites of action is not well understood.

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Purpose: Considering the recent implementation of lung cancer screening guidelines, it is crucial that small pulmonary nodules are accurately diagnosed. There is a significant need for quick, precise, and minimally invasive biopsy methods, especially for patients with small lung lesions in the outer periphery. Robotic bronchoscopy (RB) has recently emerged as a novel solution.

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Gestational diabetes mellitus (GDM) is a metabolic complication that manifests as hyperglycemia during the later stages of pregnancy. In high resource settings, careful management of GDM limits risk to the pregnancy, and hyperglycemia typically resolves after birth. At the same time, previous studies have revealed that the gut microbiome of infants born to mothers who experienced GDM exhibit reduced diversity and reduction in the abundance of several key taxa, including .

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