Publications by authors named "J P Combe"

Objective: Pharmacy work encompasses two main streams. These are logistic flow (the supply and distribution of healthcare products) and pharmaceutical flow (the dispensing and provision of pharmacy services). The pharmaceutical flow has increased significantly with the introduction of reimbursed services such as Rapid Diagnostic Tests, chronic disease screening, minor ailment prescriptions, vaccine prescription and administration, and medication reviews.

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Mismatch repair (MMR) deficiency can be indicative of Lynch syndrome (LS) and guide treatment with immune checkpoint inhibitors. Colorectal cancers (CRCs) and endometrial cancers (ECs) are routinely screened to identify LS, primarily using immunohistochemistry (IHC) or microsatellite instability (MSI) testing, but concordance between these methods is variable in ECs. Here, we investigate this variability in 361 ECs from the Ohio OCCPI/OPTEC ( = 196) and Manchester PETALS ( = 165) trials, where concordance between assays differed significantly.

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Article Synopsis
  • New technologies for managing type 1 diabetes (T1D) in young children are growing, but there’s a lack of real-life studies focused on kids under 6 years old.
  • The study aimed to investigate parental satisfaction with continuous and flash glucose monitoring devices for T1D in children, involving 114 parents who completed a questionnaire.
  • Results showed 95% of parents were satisfied with the monitoring devices, with satisfaction linked to the device's reliability, though some parents reported challenges related to applying the devices and skin reactions.
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Introduction: The prevalence of type 1 diabetes is increasing worldwide. The advent of new monitoring devices has enabled tighter glycemic control.

Aim: To study the impact of glucose monitoring devices on the everyday life of young children with type 1 diabetes (T1D) and their parents.

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Almost one third of kidney donation candidates are incompatible (HLA and/or ABO) with their directed recipient. Kidney paired donation allows potential donors to be exchanged and gives access to a compatible kidney transplant. The Bioethics Law of 2011 authorised kidney paired donation in France with reciprocity between 2 incompatible "donor-recipient" pairs.

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