Publications by authors named "J P Chagnon"
There is a growing interest in the quality of work life (QWL) of healthcare professionals and staff well-being. We decided to measure the perceived QWL of ICU physicians and the factors that could influence their perception. We performed a survey coordinated and executed by the French Trade Union of Intensive Care Physicians (SMR).
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- Climate change is projected to significantly increase temperature-related mortality in Canada by 2099, with a notable rise of 17.31% in deaths expected under high greenhouse gas emissions scenarios.
- The study analyzed non-accidental mortality data from 2000 to 2015 across 111 health regions, considering age demographics and population growth effects on mortality rates due to temperature fluctuations.
- The highest mortality increases are predicted for older adults (65+) and in scenarios with rapid aging populations, highlighting the importance of implementing strong climate policies to mitigate these impacts.
Rationale: A decade after drotrecogin alfa (activated) (DAA) was released on the market worldwide, its benefit-to-risk ratio remains a matter of debate.
Objectives: The current investigator-led trial was designed to evaluate the efficacy and safety of DAA, in combination with low-dose steroids, in adults with persistent septic shock.
Methods: This was a multicenter (24 intensive care units), placebo-controlled, double-blind, 2 × 2 factorial design trial in which adults with persistent septic shock and no contraindication to DAA were randomly assigned to DAA alone (24 μg/kg/h for 96 h), hydrocortisone and fludrocortisone alone, their respective combinations, or their respective placebos.
Objective: We hypothesized that the hemodynamic response to a deep inspiration maneuver (DIM) indicates fluid responsiveness in spontaneously breathing (SB) patients.
Design: Prospective study.
Setting: ICU of a general hospital.