Publications by authors named "J P Bleton"

Background: Transcranial Direct Current Stimulation (tDCS) of the cerebellum shows promise for the treatment of dystonia. Specific motor rehabilitation programs have also been developed in this context. However, the combination of these two approaches has not yet been evaluated to determine their therapeutic potential.

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Article Synopsis
  • Cervical dystonia leads to involuntary muscle contractions, causing abnormal head and neck postures, with botulinum neurotoxin being the primary treatment option.
  • A study compared 10 individuals with cervical dystonia to 10 healthy participants, using cone-beam CT to assess head posture and rotational movement of the cervical spine.
  • Findings revealed that those with cervical dystonia had significantly altered head posture and reduced rotational motion in the cervical spine, particularly affecting the upper cervical region, highlighting the need for targeted treatment of the involved muscles.
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M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in species. This strain abundantly produces the blue polyketide antibiotic, actinorhodin (ACT), and has a low lipid content. In a process designed to delete the gene encoding the isocitrate lyase () of the glyoxylate cycle, an unexpected variant of was obtained besides deletion mutants.

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After life in utero and birth, the skin is submitted to an important process of adaptation to a relatively dry gaseous environment. Skin surface lipids (SSLs) contribute actively to the protection of the skin barrier. Within this context, our objective was to study the evolution of each lipid compound during the postnatal period.

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