Publications by authors named "J P Blackwell"
Background: Autistic children can experience mental health, social and emotional difficulties. Carol Gray's Social Stories™ are a highly personalised intervention that provide social information in a short individually tailored story.
Methods: A multi-site pragmatic cluster randomised controlled trial to evaluate the clinical and cost-effectiveness of Social Stories™ alongside care as usual in autistic children aged 4-11 years.
Article Synopsis
- BFL1, an antiapoptotic protein from the BCL2 family, is linked to hematological cancers but hasn't been extensively researched.
- Two articles present the development of selective BFL1 inhibitors, starting from hit identification using a covalent fragment library and leading to optimized compounds.
- One compound not only induced cell death in specific cancer cell lines but also stabilized the BFL1 protein, significantly increasing its half-life to 10.8 hours while activating cellular apoptosis markers.
Background: The authors present a cadaveric validation of a minimally invasive articular cartilage preserving olecranon osteotomy technique for use in the operative management of distal humeral fractures.
Methods: Twenty-four elbows in six male and six female formaldehyde embalmed cadavers were dissected. With the cadaver placed in a lateral decubitus position, a posterior sub-periosteal dissection was performed to the medial and lateral aspects of the olecranon at the level of the joint and Mini Hohmann retractors were inserted into each side of the ulnohumeral joint.
Challenges to Contemporary Wide Complex Tachycardia Criteria: A Single-center Case Series of 1:1 Atrial Flutter.
J Innov Card Rhythm Manag
October 2024
Atrial flutter with 1:1 atrioventricular conduction is a rare cause of wide complex tachycardia, which presents a diagnostic challenge. This report describes a series of eight cases of 1:1 atrial flutter compiled during 2018-2022. The cases in this report include patients without class 1 anti-arrhythmic use or pre-excitation.
View Article and Find Full Text PDFBackground: Many nurses report feeling underprepared and insecure about the mandated reporting of concern for child maltreatment, which is further compounded by parental disability.
Purpose: This scoping review examined the body of literature on nurse mandated reporting responsibility within the context of parental disability.
Methods: A scoping review was conducted as informed by the Arksey and O'Malley Framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews.