Publications by authors named "J P Bassand"
Background: Oral anticoagulants (OAC) are underutilized in older patients with atrial fibrillation, despite proven clinical benefits. Our objective was to investigate baseline characteristics, treatment patterns, and impact of anticoagulation upon clinical outcomes with respect to age.
Methods: Adults with newly diagnosed atrial fibrillation were recruited into the prospective observational registry, GARFIELD-AF, and followed up for 24 months.
Background: An unmet need exists to reliably predict the risk of intracranial hemorrhage (ICH) in patients with atrial fibrillation (AF) treated with oral anticoagulants (OACs).
Hypothesis: An externally validated model improves ICH risk stratification.
Methods: Independent factors associated with ICH were identified by Cox proportional hazard modeling, using pooled data from the GARFIELD-AF (Global Anticoagulant Registry in the FIELD-Atrial Fibrillation) and ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) registries.
Article Synopsis
- This study investigates how diabetes mellitus (DM) affects the management and outcomes of patients with newly diagnosed atrial fibrillation (AF) and evaluates the impact of oral anticoagulation (OAC) on these patients.
- The research analyzed data from over 52,000 patients in the GARFIELD-AF registry, comparing those with DM and those without, while focusing on how OAC use influenced their mortality and stroke risks.
- Findings showed that both DM and non-DM patients experienced lower risks of death and stroke with OAC, while patients with insulin-requiring DM saw significant benefits from OAC usage, despite an increased risk of major bleeding.*
Aims: This study aimed to identify relationships in recently diagnosed atrial fibrillation (AF) patients with respect to anticoagulation status, use of guideline-directed medical therapy (GDMT) for comorbid cardiovascular conditions (co-GDMT), and clinical outcomes. The Global Anticoagulant Registry in the FIELD (GARFIELD)-AF is a prospective, international registry of patients with recently diagnosed non-valvular AF at risk of stroke (NCT01090362).
Methods And Results: Guideline-directed medical therapy was defined according to the European Society of Cardiology guidelines.
Objective: There is a substantial incidence of stroke in patients with atrial fibrillation (AF) not receiving anticoagulation. The reasons for not receiving anticoagulation are generally attributed to clinician's choice, however, a proportion of AF patients refuse anticoagulation. The aim of our study was to investigate factors associated with patient refusal of anticoagulation and the clinical outcomes in these patients.
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