It all began in Issaquah 50 years ago.

"Somehow scientists still pursue the same questions, if now on higher levels of theoretical abstraction rooted in deeper layers of empirical evidence… To paraphrase an old philosophy joke, science is more like it is today than it has ever been. In other words, science remains as challenging as ever to human inquiry. And the need to communicate its progress… remains as essential now as then.

Pains Revisited.

Objectives: The management of pain patients has not evolved as rapidly as envisioned when IASP was founded almost 50 years ago. We sought to identify factors that could contribute to this situation, with a focus on concepts of pain and the education of pain physicians.

Methods: Relevant literature describing new strategies for diagnosing and managing patients with high-impact chronic pain was reviewed.

Assessment and report of individual symptoms in studies of delirium in postoperative populations: a systematic review.

Objectives: Delirium is most often reported as present or absent. Patients with symptoms falling short of the diagnostic criteria for delirium fall into 'no delirium' or 'control' groups. This binary classification neglects individual symptoms and may be hindering identification of the pathophysiology underlying delirium.

Risk factors for femoral stem fracture following total hip arthroplasty: a systematic review and meta analysis.

Background: Femoral stem fracture following total hip arthroplasty (THA) is an infrequent but nevertheless devastating complication, with an increasing worldwide prevalence as demand for primary THA continues to increase. The aim of this study was to perform a systematic review and meta-analysis of risk factors for femoral stem fracture to help identify at risk patients.

Methods: A systematic search was conducted on EMBASE, MEDLINE and AMED to identify relevant studies.