Publications by authors named "J P Baikova"

Crohn's disease (CD) is a type of inflammatory bowel disease (IDB). The endoscopic picture of Crohn's disease includes thickened submucosa, transmural inflammation, fissuring ulceration, and non-caseating granulomas. Intestinal microbiome dysbiosis has been described systematically in patients with IBD.

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One of the dysbioses often observed in Crohn's disease (CD) patients is an increased abundance of (10-100 fold compared to healthy individuals) (Gevers et al., 2014). The data reported is a large-scale proteome profile for isolates collected from CD patients and healthy individuals.

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Article Synopsis
  • Crohn's disease is linked to imbalances in gut bacteria, specifically with an increase in certain types of E. coli, and more research is needed to understand their role.
  • A metagenomic study of Crohn's patients showed that the gut microbiomes varied significantly between individuals, revealing high genetic diversity in E. coli strains.
  • The findings suggest that understanding the genetic diversity of these bacteria can help develop better prevention and treatment options for Crohn's disease.
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Background: Escherichia coli (E. coli) has been increasingly implicated in the pathogenesis of Crohn's disease (CD). The phylogeny of E.

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We studied homing and differentiation fate of transplanted bone marrow mononuclears after non-selective intracoronary injection on day 30 after acute myocardial infarction in rats. Mononuclear cells migrated to the cicatrix zone where they differentiated into fibroblasts and myofibroblasts. Mononuclear cells did not differentiate into cardiomyocytes, endothelial cells, or smooth muscle cells of vascular media.

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