Publications by authors named "J P B Viola"
Coronavirus disease 2019 (COVID-19) still causes death in elderly and immunocompromised individuals, for whom the sustainability of the vaccine response may be limited. Antiviral treatments, such as remdesivir or molnupiravir, have demonstrated limited clinical efficacy. Nirmatrelvir, an acute respiratory syndrome coronavirus 2 (SARS-CoV-2) major protease inhibitor, is clinically effective but has been associated with viral rebound and antiviral resistance.
View Article and Find Full Text PDFReintegration Following Amputation: A Biopsychosocial Approach.
Phys Med Rehabil Clin N Am
November 2024
Article Synopsis
- Reintegration after limb loss depends on the interplay of mental health, environmental factors, and physical aspects like pain and prosthetic use.
- While some individuals successfully adapt and experience personal growth, others face significant challenges during this transition.
- Interdisciplinary teams play a crucial role by identifying and addressing barriers early on, helping amputees return to normal activities like driving more swiftly, which enhances overall quality of life.
Article Synopsis
- Scientists are studying how tiny structures in the kidneys form during development, especially how they branch out and work together.
- They discovered that as these structures grow, they get packed tightly together, which can change how the cells make decisions.
- The researchers used experiments and math to understand this packing and found that it affects how the kidneys develop over time in mice and might help in creating new tissues for medical purposes.
Cell patterning for 3D culture has increased our understanding of how cells interact among themselves and with their environment during tissue morphogenesis. Building cell communities from the bottom up with size and compositional control is invaluable for studies of morphological transitions. Here, we detail Photolithographic DNA-programmed Assembly of Cells (pDPAC).
View Article and Find Full Text PDFThe relay feedback auto-tuning method, which was an early commercialized approach, has maintained its popularity due to its simplicity and robustness. However, the classical proportional integral derivative (PID) controller auto-tuning method often results in unacceptable overshoot, especially for integrating and higher-order processes. By integrating the TID controller with the relay feedback technique, we significantly enhance dynamic control performance without relying on prior knowledge of the system.
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