[Management of opioid-induced constipation : the old and the new].

The use of opioids has increased over the past 20 years. Among their side effects, constipation is probably the most common. Managing opioid-induced constipation primarily involves laxatives from the onset and addressing any additional causes of constipation.

Diffusion tensor imaging changes of the cortico-thalamic-striatal tracts correlate with fatigue and disability in people with relapsing-remitting MS.

Purpose: To investigate how the microstructural neural integrity of cortico-thalamic-striatal (CTS) tracts correlate with fatigue and disability over time. The primary outcome was diffusion tensor imaging (DTI) metrics change over time, and the secondary outcome was correlations with fatigue and disability in people with RRMS (pw-RRMS).

Methods: 76 clinically stable pw-RRMS and 43 matched healthy controls (HCs).

Determination of hepatic extraction fraction with gadoxetate low-temporal resolution DCE-MRI-based deconvolution analysis: validation with ALBI score and Child-Pugh class.

Introduction: In this study, we aimed to investigate the feasibility of gadoxetate low-temporal resolution (LTR) DCE-MRI for voxel-based hepatic extraction fraction (HEF) quantification for liver sparing radiotherapy using a deconvolution analysis (DA) method.

Methods: The accuracy and consistency of the deconvolution implementation in estimating liver function was first assessed using simulation data. Then, the method was applied to DCE-MRI data collected retrospectively from 64 patients (25 normal liver function and 39 cirrhotic patients) to generate HEF maps.

Neural diffusion tensor imaging metrics correlate with clinical measures in people with relapsing-remitting MS.

Background And Purpose: Diffusion tensor imaging (DTI) can detect microstructural changes of white matter in multiple sclerosis (MS) and might clarify mechanisms responsible for disability. Thus, we aimed to compare DTI metrics in relapsing-remitting MS patients (RRMS) with healthy controls (HCs), and explore the correlations between DTI metrics, total brain white matter (TBWM) and white matter lesion (WML) with clinical parameters compared to volumetric measures.

Material And Methods: 37 RRMS patients and 19 age/sex-matched HCs were included.

Disadvantage of the FDM method for printing protective masks against COVID-19 and solution.

Outages in the supply of basic medical supplies and protective equipment have led to efforts to replace them. The team of BUT employees and students has developed a protective half mask that can also be printed on a standard 3D printer without the use of special materials. The original half mask is intended as an improvised protection that can be easily printed on standard 3D printers with FDM technology.