Multisite Is Superior to Single-Site Intratumoral Chemotherapy to Retard the Outcomes of Pancreatic Ductal Adenocarcinoma in a Murine Model.

Introduction: Locally advanced unresectable pancreatic cancer (LAPC) has a dismal prognosis, with intratumoral therapies showing limited benefits. We assume that the dense stroma within these tumors hampers drug dispersion.

Aim: This study explores the efficacy of multisite intratumoral injections in improving a drug's distribution while minimizing its side effects.

Intestinal electrical stimulation decreases postprandial blood glucose levels in rats.

Background: Reducing postprandial blood glucose concentrations in diabetic patients might contribute to optimal glycemic control. Gastrointestinal electrical stimulation has been proposed as a novel therapy for both gastrointestinal motility disorders and obesity. The present study investigated the effects and underlying mechanisms of intestinal electrical stimulation (IES) on postprandial blood glucose levels in rats.

Finding shape axes using magnetic fields.

This paper presents a novel method, based on magnetic field principles, for obtaining the axes of shapes. The method is based on directional information of the shape's boundary. By simulating a parallel algorithm, we are able to generate the inner as well as the outer axes (axes of concavities) of the shape.

Estimation of 3-D motion using eigen-normalization and expansion matching.

This correspondence describes a novel approach to three-dimensional (3-D) motion estimation of planar objects based on eigen-normalization, expansion matching (EXM), and a scaled orthographic projection model. Our approach leads to a comprehensive temporal description of all the degrees of freedom in 3-D (three rotations and three translations). Experiments with video streams show robust estimation of the real 3-D rotations and translations of the objects in motion.

Generalized feature extraction using expansion matching.

A novel generalized feature extraction method based on the expansion matching (EXM) method and on the Karhunen-Loeve transform (KLT) is presented. The method provides an efficient way to locate complex features of interest like corners and junctions with reduced number of filtering operations. The EXM method is used to design optimal detectors for a set of model elementary features.