Publications by authors named "J Orne-Gliemann"
Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries.
Trop Med Int Health
November 2024
Objectives: Chest x-ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource-limited settings. Digital CXR (d-CXR) can solve some image quality issues and facilitate their transfer for quality control. We assess the implementation of introducing d-CXR in 12 district hospitals (DHs) in 2021-2022 across Cambodia, Cameroon, Ivory Coast, Mozambique, Sierra Leone and Uganda as part of the TB-speed decentralisation study on childhood TB diagnosis.
View Article and Find Full Text PDFEffect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study.
EClinicalMedicine
April 2024
Article Synopsis
- Childhood tuberculosis (TB) is often underdiagnosed due to low awareness and limited access to necessary diagnostic tools in healthcare settings.
- An operational research study in several African and Asian countries tested a comprehensive diagnostic approach by decentralizing TB diagnostics to district hospitals and primary health centers for children under 15 years old.
- The intervention significantly increased TB detection rates, with diagnoses rising from 0.08% pre-intervention to 0.23% during the intervention, highlighting the effectiveness of decentralized health services.
Acceptability of decentralizing childhood tuberculosis diagnosis in low-income countries with high tuberculosis incidence: Experiences and perceptions from health care workers in Sub-Saharan Africa and South-East Asia.
PLOS Glob Public Health
October 2023
Article Synopsis
- * A study in various African countries assessed healthcare workers' experiences with a comprehensive tuberculosis diagnosis package, highlighting that while systematic screening increased awareness, it also increased their workload.
- * Healthcare workers generally felt confident with certain diagnostic procedures like nasopharyngeal aspirations and molecular testing, but expressed concerns about logistical issues, cultural barriers for stool collection, and the need for ongoing training to improve self-efficacy in clinical evaluations.
Acceptability and feasibility of home and hospital follow-up in Burkina Faso and Guinea: A mixed-method study among patients of the COVID-19 Coverage-Africa clinical trial.
PLOS Glob Public Health
July 2023
Patient experiences and perspectives on trial participation and follow-up may influence their compliance with research procedures or negatively impact their well-being. We aimed to explore the acceptability and feasibility of home-based and hospital-based follow-up modalities among COVID-19 patients enrolled in the ANTICOV ANRS COV33 Coverage-Africa trial in Burkina Faso and Guinea. The trial (2021-2022) evaluated the efficacy of treatments to prevent clinical worsening among COVID-19 patients with mild to moderate symptoms.
View Article and Find Full Text PDFProtocol: Implementation evaluation of a combination intervention for sustainable blood pressure control in rural KwaZulu-Natal, South Africa (IMPACT BP): A three-arm, unblinded, parallel group individually randomized clinical trial.
Contemp Clin Trials
August 2023
Background: Hypertension is the primary risk factor for stroke and heart disease, which are leading causes of death in South Africa. Despite the availability of treatments, there is an implementation gap in how best to deliver hypertension care in this resource-limited region.
Methods: We describe a three-arm parallel group individually randomized control trial to evaluate the effectiveness and implementation of a technology-supported, community-based intervention to improve blood pressure control among people with hypertension in rural KwaZulu-Natal.