Three methods for investigating, assessing and supporting the normal and pathological gait and manipulation activity.

Three methods to describe biped locomotion as well as manipulation activity are presented. Methods using so-called couple oscillators as rhythm generators are described. Based on a mathematical model, results of computer simulation of biped locomotion are presented.

Gangliosides improve the outcome of experimental allergic neuritis (EAN).

The effect of gangliosides on the clinical expression of experimental allergic neuritis (EAN), a PNS counterpart of experimental allergic encephalomyelitis (EAE), was tested in Lewis rats sensitized with bovine intradural root myelin in complete Freund's adjuvant (CFA). A mixture of bovine brain gangliosides (GM1, GD1a, GD1b, GT1b) was injected intramuscularly at a daily dose of 20 mg per kg beginning 6 days post inoculation. The results show that GA treatment considerably reduces the incidence of mortality, delays its occurrence, and reduces the severity of clinical scores when either the whole population or survivors only are considered.