Publications by authors named "J Obata"
Deep caries and severe periodontitis cause bone resorption in periodontal tissue, and severe bone resorption leads to tooth loss. Periodontal ligament stem cells (PDLSCs) are important for the healing of defective periodontal tissue. It is increasingly understood that healing of periodontal tissue is mediated through the secretion of trophic factors, particularly exosomes.
View Article and Find Full Text PDFWe aimed to evaluate the materials based on 4-methacryloxyethyl trimellitate anhydride/methyl methacrylate tri-n-butylborane (Super-bond [SB]) and nano hydroxyapatite (naHAp) for the repair of perforation at pulp chamber floor (PPF) in vitro and in vivo models. SB and naHAp were mixed in the mass ratio of 10% or 30% to produce naHAp/SB. Human periodontal ligament stem cells (HPDLSCs) were cultured on resin discs of SB or naHAp/SB to analyze the effects of naHAp/SB on cell adhesion, proliferation, and cementoblastic differentiation.
View Article and Find Full Text PDFArticle Synopsis
- - This study investigates the predictive ability of CHADS, CHADS-VASc, and R-CHADS scores for major adverse cardiac events (MACE) in patients with non-ST-elevation myocardial infarction (NSTEMI) who underwent percutaneous coronary intervention (PCI).
- - A total of 440 NSTEMI patients were tracked for up to 3 years, with findings showing that 12.5% experienced MACE, indicating a notable risk associated with higher scoring on these predictive scales.
- - The results reveal that higher scores correlate with a greater likelihood of MACE, as supported by Kaplan-Meier analysis, highlighting the importance of these scores in assessing the prognosis of NSTEMI patients.
Background: Patients who undergo percutaneous coronary intervention (PCI) with rotational atherectomy (RA) are at high risk of adverse clinical outcomes, and there are few clinical risk stratification tools for these patients.
Methods: We conducted a study with 196 patients who underwent PCI with RA out of 7391 patients who underwent PCI using a multicenter, prospective cohort registry. Patients were divided into three groups according to the tertiles of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention (TRS 2°P): 65 patients in the T1 group (TRS 2°P < 3), 66 patients in the T2 group (TRS 2°P = 3), and 65 patients in the T3 group (TRS 2°P > 3).