Publications by authors named "J O Jarden"

Background: It is recommended that people with gliomas engage in rehabilitation, but high-quality evidence to support this recommendation is lacking.

Objective: This study assesses the effectiveness of a physical therapy- and occupational therapy-based rehabilitation intervention compared with usual rehabilitation care for quality of life (QoL) during active anticancer treatment.

Design: This study was a randomized controlled trial.

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Article Synopsis
  • The study examines how the location of glioma tumors in the right or left hemisphere impacts patients' health-related quality of life and functional performance during early treatment stages.
  • It involved 81 adult patients analyzed during their first week of chemo-radiation, with results showing no significant differences in overall quality of life between the groups, but variations in specific symptoms and functional abilities.
  • Key findings indicate that left hemisphere lesions were linked to more communication deficits, while right hemisphere lesions were associated with more frequent headaches and difficulties in everyday task management, as well as possible increased fatigue in patients with right-sided Glioblastoma Multiforme.
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Purpose: This report aims to assess the safety and feasibility of using an interdisciplinary rehabilitation intervention for a future randomized controlled trial in patients with gliomas in the initial treatment phase.

Method: We conducted an outpatient two-part rehabilitation intervention that involved six weeks of therapeutic supervised training (part one) and six weeks of unsupervised training in a local gym following a training protocol (part two).

Results: Predefined feasibility objectives of safety (100%), consent rate (>80%), drop-out (<20%), adherence (>80%) and patient satisfaction (>80%) was achieved at part one.

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Diaschisis denotes brain dysfunction remote from a focal brain lesion. We have quantified diaschisis and investigated its prognostic value in glioma. We compared 50 F-FDG PET/CT studies collected prospectively from 14 patients with supratentorial glioma (5 men and 9 women; age range, 35-77 y) with 10 single scans from healthy controls (age range, 43-75 y).

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Introduction: Gliomas are among the biggest challenges in neurological and oncology rehabilitation and optimising treatment is of major clinical importance in this population. Although inpatient rehabilitation among glioma patients' results in improved functional measures, rehabilitation efforts are still not emphasised in this patient group and the literature lacks studies investigating the impact of outpatient rehabilitation.

Method: This protocol describes a randomised 6-week parallel group rehabilitation study investigating an outpatient interdisciplinary rehabilitation programme.

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