Publications by authors named "J O'B Hourihane"
Neutrophils are short-lived cells of the innate immune system and represent 50-70% of the circulating leucocytes. Their primary role is antimicrobial defence which they accomplish through rapid migration to sites of inflammation followed by phagocytosis, degranulation and the release of neutrophil extracellular traps (NETosis). While previously considered terminally-differentiated cells, they have been shown to have great adaptability and to play a role in conditions ranging from cancer to autoimmunity.
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- Precautionary Allergen Labelling (PAL) is used to warn people about possible allergens in food that could affect those with allergies.
- The World Allergy Organization found that PAL is not consistently regulated, which makes it confusing for people with food allergies.
- There are discussions among global organizations to create better rules for PAL so that it is clear and helpful for everyone, but there are still some challenges to making these rules work everywhere.
Background: Complete avoidance of milk is the usual management for IgE-mediated cow's milk protein allergy (CMPA). A baked milk ladder is a method of dietary advancement therapy in IgE-mediated CMPA in Ireland, while in Spain, avoidance of milk awaiting natural tolerance acquisition through an oral food challenge (OFC) is employed. The aim of this study was to evaluate the use of dietary advancement therapy using a milk ladder compared with complete avoidance of milk for managing IgE-mediated CMPA.
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