Publications by authors named "J Nunez-Garcia"
BackgroundAntimicrobial resistance (AMR) is a global threat. Monitoring using an integrated One Health approach is essential to detect changes in AMR occurrence.AimWe aimed to detect AMR genes in pathogenic and commensal collected 2013-2020 within monitoring programmes and research from food animals, food (fresh retail raw meat) and humans in six European countries, to compare vertical and horizontal transmission.
View Article and Find Full Text PDFDisinfectants are essential for biosecurity, preventing the persistence and spread of zoonotic pathogens on farms and subsequent human infections. In this study, transcriptomics and genomics were utilised to assess the effect of disinfectant exposure on pathogenic . The exposure of O157:H7 to sub-optimal concentrations of commonly used farm disinfectants elicited changes in both the transcriptome and genome.
View Article and Find Full Text PDFArticle Synopsis
- Surveillance is crucial for tracking the rise of antimicrobial resistance (AMR) in bacteria, especially as it can spread from livestock to humans through the food chain.
- This study used whole genome sequencing to analyze E. coli samples from poultry in the UK, revealing shifts in the dominant AMR genes over time, particularly with increases in diversity by 2020.
- The findings emphasize the importance of ongoing genomic monitoring to understand AMR dynamics and facilitate cross-country comparisons, ultimately aiding in identifying and addressing emerging threats.
Article Synopsis
- Left atrial appendage occlusion (LAAO) is a successful alternative to oral anticoagulants for patients with nonvalvular atrial fibrillation, and advancements in technology have made the procedure safer and more efficient.* -
- This study aimed to compare the safety and efficacy of an outpatient LAAO program versus a conventional hospital stay approach by analyzing 262 patients and measuring their outcomes after 30 days.* -
- Results showed a 99.6% success rate and similar safety profiles between the outpatient and conventional groups, with the outpatient group benefiting from a shorter hospital stay, indicating potential clinical and economic advantages.*