Publications by authors named "J Nunez-Cortes"
The aim of this study was to analyze whether the coronavirus disease 2019 (COVID-19) vaccine reduces mortality in patients with moderate or severe COVID-19 disease requiring oxygen therapy. A retrospective cohort study, with data from 148 hospitals in both Spain (111 hospitals) and Argentina (37 hospitals), was conducted. We evaluated hospitalized patients for COVID-19 older than 18 years with oxygen requirements.
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- New SARS-CoV-2 variants, breakthrough infections, waning immunity, and low vaccination rates are causing increased hospitalizations and deaths, highlighting the need for better resource allocation tools in hospitals, especially in resource-limited areas.
- The CODOP tool, developed using machine learning, predicts the clinical outcomes of hospitalized COVID-19 patients by analyzing 12 clinical parameters, demonstrating high accuracy levels (AUROC: 0.90-0.96) before clinical resolution.
- CODOP's effectiveness is consistent across different virus variants and vaccination statuses, and it includes online calculators for efficient patient triage, validated through extensive testing in Latin America.
Objective: To compare coronavirus disease 2019 (COVID-19) hospitalization outcomes between persons with and without HIV.
Design: Retrospective observational cohort study in 150 hospitals in Spain.
Methods: Patients admitted from 1 March to 8 October 2020 with COVID-19 diagnosis confirmed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 positive) PCR test in respiratory tract samples.
Background: Since December 2019, the COVID-19 pandemic has changed the concept of medicine. This work aims to analyze the use of antibiotics in patients admitted to the hospital due to SARS-CoV-2 infection.
Methods: This work analyzes the use and effectiveness of antibiotics in hospitalized patients with COVID-19 based on data from the SEMI-COVID-19 registry, an initiative to generate knowledge about this disease using data from electronic medical records.
Objectives: Since the results of the RECOVERY trial, WHO recommendations about the use of corticosteroids (CTs) in COVID-19 have changed. The aim of the study is to analyse the evolutive use of CTs in Spain during the pandemic to assess the potential influence of new recommendations.
Material And Methods: A retrospective, descriptive, and observational study was conducted on adults hospitalised due to COVID-19 in Spain who were included in the SEMI-COVID-19 Registry from March to November 2020.