Publications by authors named "J Nicoli"
A Mixture of Four Probiotic Strains (Probiatop®) Mitigates Food Allergy to Ovalbumin in Mice.
Vivian C Miranda Ramon O Souza Bruno Gallotti Marcos F A de Oliveira Ana Maria C Faria Jacques R Nicoli
Probiotics Antimicrob Proteins
October 2024
Article Synopsis
- Food allergy results from a breakdown in the body's ability to tolerate certain foods, leading to various symptoms ranging from mild discomfort to severe reactions like anaphylaxis.
- Current treatment mainly involves eliminating trigger foods, which can harm nutrition and impact social life, highlighting the need for alternative therapies.
- The study examines the probiotic blend Probiatop®, showing that it can reduce allergy symptoms, improve gut health, and positively affect gut bacteria in models of food allergy to ovalbumin.
Asthma prevalence has been increasing in communities that become more urbanised. Our previous results showed that Saccharomyces cerevisiae UFMG A-905 prevented the development of asthma symptoms and characteristics in a dose-dependent manner. Perinatal programming theory proposes that early exposure to some stimuli may have a protective effect in adult life.
View Article and Find Full Text PDFOral Treatment with Saccharomyces cerevisiae CNCM I-3856 Mitigates the Inflammatory Response Experimentally Induced by Salmonella enterica subsp. enterica Serovar Typhimurium in Mice.
Lara L Campos Samantha R M Oliveira Maisa N S Amaral Bruno Gallotti Aline F Oliveira Jacques R Nicoli
Probiotics Antimicrob Proteins
September 2024
Article Synopsis
- Salmonella spp. cause a range of diarrheal diseases and pose a public health threat, with this study focusing on the therapeutic effects of the yeast Saccharomyces cerevisiae CNCM I-3856 in mice infected with Salmonella Typhimurium.
- The study found that mice treated with the yeast showed reduced mortality and weight loss compared to control mice, suggesting S. cerevisiae's potential benefits in managing Salmonella infections.
- The yeast improved immune responses, reduced intestinal permeability, and lowered inflammation, leading to less severe liver and intestinal damage, indicating its promising role as a therapeutic agent against Salmonella-induced infections.
Background: The administration of probiotics has been shown to be beneficial in asthma. The administration of UFMG A-905 prevented asthma development. Traditionally, probiotics are administered using dairy-based matrices, but other vehicles (e.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed the bacterial and fungal diversity in kefir drinks made with milk or sugared water, sourced from different Brazilian cities, by sequencing their RNA transcripts.
- Both types of kefir contained common bacterial families but differed in yeast presence, with more Saccharomycetaceae in water kefir and Dipodascaceae and Pichiaceae in milk kefir.
- Although the kefir samples had varying microbial communities, their functional processes were similar, showcasing differences mainly in energy metabolism and genetic information processing between the two types.