Effects of caffeine on anaerobic exercise in boys.

The effects of caffeine on anaerobic exercise in young boys was investigated. Twenty-four healthy 8-10 year old boys participated in a randomized double-blind, double-crossover, counter-balanced study. Each subject received the caffeinated drink (CAF--5 mg · kg(-1)) or placebo (PL) twice each on four separate visits.

Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts.

Eukaryotes are endowed with multiple specialized DNA polymerases, some (if not all) of which are believed to play important roles in the tolerance of base damage during DNA replication. Among these DNA polymerases, Rev1 protein (a deoxycytidyl transferase) from vertebrates interacts with several other specialized polymerases via a highly conserved C-terminal region. The present studies assessed whether these interactions are retained in more experimentally tractable model systems, including yeasts, flies, and the nematode C.