Background: Melioidosis, caused by Burkholderia pseudomallei, is an important disease that is endemic in areas of northern Australia and can cause a wide range of clinical signs in people and animals. There is limited published data on the disease in marsupials.
Case Report: Two captive red-legged pademelons (Thylogale stigmatica) with collective signs of lethargy, dysphagia and bloody oral discharge were submitted for necropsy and showed variations in pathology findings ranging from multifocal abscessation in various tissues to evidence of fulminant septicaemia.
J Gerontol A Biol Sci Med Sci
December 2024
As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28-30, 2024, was hosted by The Ohio State University in Columbus, Ohio and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms.
View Article and Find Full Text PDFOpen Forum Infect Dis
December 2024
Background: Hepatitis C virus (HCV) guidelines recommend direct-acting antiviral (DAA) rescue regimens in cases of treatment failure, and first-line regimens for reinfection. In patients with barriers to follow-up after treatment, it is difficult to determine if HCV viremia represents failure or reinfection. Patients are often retreated with rescue regimens despite higher costs.
View Article and Find Full Text PDFBackground: Frontoorbital distraction osteogenesis (FODO) is an established surgical technique for patients with unicoronal craniosynostosis. The authors' institution has used an endoscope-assisted technique (endo-FODO) in recent years to decrease cutaneous scarring and lessen the impact on the functional growth matrix. This study compared perioperative outcomes in patients undergoing endo-FODO to those in patients undergoing the traditional coronal approach.
View Article and Find Full Text PDF