Publications by authors named "J Nevoux"

Article Synopsis
  • The study investigates hearing loss in patients with pseudohypoparathyroidism (PHP) and related disorders, which typically show symptoms like short stature and bone abnormalities during childhood.
  • Conducted at Bicêtre Paris-Saclay Hospital, the research analyzed patient data for auditory health and established that 39% of the participants experienced hearing impairment.
  • Significant predictors of hearing loss identified were short stature and ectopic ossifications, while factors such as sex, BMI, and specific genetic mutations showed no correlation.
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Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient's medical management (outpa-tient care, standard hospital admission, and ICU admission).

Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing.

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X-linked hypophosphatemic rickets (XLH) is a genetic cause of renal hypophosphatemia due to inactivation of the PHEX gene, with an inappropriate concentration of fibroblast growth factor 23 (FGF23). Burosumab, an anti-FGF23 monoclonal antibody, is a validated treatment for XLH, but its use in patients with chronic kidney disease (CKD) has not been validated. A 61-year-old man with XLH developed CKD during follow-up.

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Purpose: Hearing rehabilitation through middle ear surgery can be challenging, particularly for patients with chronic otitis media, but new hearing devices offer opportunity to reach this goal. The aim was to compare hearing outcomes and quality of life in patients who were converted from a Baha Attract system to the Osia system.

Methods: Prospective observational study, in which each subject acted as their own control.

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Background: Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by pulmonary, otological and sino-nasal manifestations. Well-defined clinical outcome measures are needed in such rare diseases research to improve follow-up and treatments. Pulmonary outcome measures have recently been described.

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