Publications by authors named "J Nesbitt"

The provision of palliative care has been seen to have a significant impact on the interprofessional health care team. Being emotionally present to support patients and families at their most stressful points in life can result in compassion satisfaction or compassion fatigue. Providing palliative care through the COVID-19 pandemic added another layer of complexity to this professional caregiving experience.

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The double-stapled () anastomotic technique associates with lower odds of anastomotic leak and stricture. , Single posterior stapled.

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Article Synopsis
  • Recent research indicates that moderate alcohol consumption may reduce the risk of neurodegenerative diseases like Alzheimer's, challenging the idea that alcohol use disorder solely harms cognitive health.
  • The study investigated the effects of moderate ethanol exposure on astrocyte function, specifically looking at the LDL receptor-related protein 1 (LRP1) and its role in modulating neuroinflammation and amyloid beta (Aβ) deposition in APP/PS1 mice.
  • Findings revealed that moderate ethanol exposure reduced levels of Aβ plaques in the brain and affected pro-inflammatory cytokines differently in male and female mice, suggesting a complex interaction between alcohol consumption, inflammation, and cognitive health.
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Facial grimacing is used to quantify spontaneous pain in mice and other mammals, but scoring relies on humans with different levels of proficiency. Here, we developed a cloud-based software platform called PainFace ( http://painface.net ) that uses machine learning to detect 4 facial action units of the mouse grimace scale (orbitals, nose, ears, whiskers) and score facial grimaces of black-coated C57BL/6 male and female mice on a 0 to 8 scale.

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African American men face chronic illness earlier in life and earlier death due to higher severity of illness and poor control of chronic diseases than their white male counterparts. Preexposure and post-exposure prophylaxis PrEP and PREP have improved the odds of survival among those living with HIV. However, the anti-retroviral treatments, though effective, are only as effective as early prevention and detection and in cases where patients can adhere to treatment regimens.

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