Publications by authors named "J Nekvindova"

Article Synopsis
  • The study investigates the phylogenetic relationships of two morphologically similar fungal genera within the Sordariomycetes, confirming they are congeneric and proposing new combinations for their classification.
  • New species were identified through molecular data, particularly using specific gene markers, as traditional morphology was insufficient for distinguishing them.
  • The research highlights the importance of the ascogenous system for genus identification and discusses the global diversity and biogeography of the genera, including the publication of whole-genome analyses to improve taxonomic standards.
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Article Synopsis
  • The study focuses on the morphological and genetic variability of certain fungi species, some of which are identified as chloridium-like asexual morphs, requiring reevaluation in taxonomy and phylogeny.
  • By analyzing 71 strains and conducting phylogenetic reconstruction using four DNA loci, the researchers identified two distinct orders and nine separate genera within a complex group of fungi.
  • The research introduces four new species and eight new combinations, offering a clearer understanding of these fungi's classification and relationships, which will aid future identification efforts.
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Article Synopsis
  • The text discusses a little-understood group of soil- and wood-inhabiting fungi that reproduce through a rare process involving multiple locations and were previously classified into three sections, but recent studies show this classification is outdated.
  • A new classification proposal is introduced, recognizing these fungi as a polythetic genus with 37 species divided into eight sections, alongside the reclassification of some species into a new genus.
  • Additionally, the study highlights the ecological role of these fungi, noting their common presence in soil, association with forest habitats, and sensitivity to climate, supported by data from the GlobalFungi database.
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The genus is a phialidic, dematiaceous hyphomycete known for its intriguing morphology and turbulent taxonomic history. This polyphasic study represents a new, comprehensive view on the taxonomy, systematics, and biogeography of and its relatives. Phylogenetic analyses of three nuclear loci confirmed that is polyphyletic.

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Background: Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in biotransformation of many drugs and other xenobiotics; however, the mechanisms responsible for their deregulation remain unclear.

Methods: We investigated a potential involvement of miRNAs in downregulation of expression of CYPs observed in HCC tumors.

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