Publications by authors named "J Neal Rutledge"

Introduction: The aim of the current study is to examine the association between life regret and well-being, through a systematic review.

Methods: Four different databases (PsycINFO, Web of Science, ProQuest, Dissertations & Theses Global, and ERIC) were used to source 31 relevant articles, published between 1989 and 2018.

Results: We conclude that experiencing greater life regret is associated with negative effects on various aspects of well-being, such as life satisfaction and depressive symptoms.

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In the ACC/AHA guidelines, the presence of symptoms plays a central role in determining timing surgery in primary mitral regurgitation (MR). Studies have shown a disconnect between the severity of MR and symptoms. The purpose of this study is to assess risk factors for symptoms in patients with chronic primary MR.

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Adolescents in the United States (US) continue to be disproportionately impacted by HIV and STIs. We investigated the associations between sexual health and substance use behaviors with HIV and STI testing among high school students in the US. Cross-sectional weighted stepwise multivariate logistic regression models were conducted to determine the odds of lifetime HIV and STI testing among students, stratified by sex.

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Article Synopsis
  • - A survey of aging researchers revealed significant disagreement on key questions about aging, such as its definition, causes, onset, and rejuvenation, indicating a lack of consensus in the field.
  • - Researchers have varying interpretations of what constitutes "aging," leading to different experimental approaches and priorities, which complicates the understanding and study of the aging process.
  • - The findings highlight the necessity for clearer definitions and targeted goals within aging research, as well as strategies to address ongoing disagreements, in hopes of advancing the field.
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The integration of quantitative trait loci (QTLs) with disease genome-wide association studies (GWASs) has proven successful in prioritizing candidate genes at disease-associated loci. QTL mapping has been focused on multi-tissue expression QTLs or plasma protein QTLs (pQTLs). We generated a cerebrospinal fluid (CSF) pQTL atlas by measuring 6,361 proteins in 3,506 samples.

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