Detailed molecular structure (XRD), conformational search, spectroscopic characterization (IR, Raman, UV, fluorescence), quantum mechanical properties and bioactivity prediction of a pyrrole analogue.

Pyrroles are an exciting class of organic compounds with immense medicinal activities. This manuscript presents the structural and quantum mechanical studies of 1-(2-aminophenyl) pyrrole using X-Ray diffraction and various spectroscopic methods like Infra-Red, Raman, Ultra-violet and Fluorescence spectroscopy and its comparison with theoretical simulations. The single-crystal X-ray diffraction values and optimized geometry parameters also were within the agreeable range.

Synthesis, Characterization and Antimicrobial Activities of Copper Derivatives of NHC-II Complexes.

Background: Caffeine, 1, 3, 7-trimethylxanthine is one of the xanthine derivatives that are for the most part utilized as a part of solutions as diuretics. The Cu (II) complexes have been synthesized from the N-heterocyclic carbene ligands.

Materials And Methods: The Cu (II) NHC complexes were characterized using analytical and spectral techniques.

Evaluation of penetration depth of 2% chlorhexidine digluconate into root dentinal tubules using confocal laser scanning microscope.

Objectives: This study evaluated the penetration depth of 2% chlorhexidine digluconate (CHX) into root dentinal tubules and the influence of passive ultrasonic irrigation (PUI) using a confocal laser scanning microscope (CLSM).

Materials And Methods: Twenty freshly extracted anterior teeth were decoronated and instrumented using Mtwo rotary files up to size 40, 4% taper. The samples were randomly divided into two groups (n = 10), that is, conventional syringe irrigation (CSI) and PUI.

Cutaneous metastases presenting as genital ulcer disease.

Cutaneous metastasis from an internal organ malignancy is rare and as, the presenting sign of malignancy is an uncommon phenomenon. Their presence, signals a poor prognosis. We report a case of 50-year-old female who was referred to sexually transmitted diseases - out patient department, with complaints of multiple genital ulcers to rule out sexually transmitted infections.

Synthesis, characterization luminiscence studies and microbial activity of ethylenediamine ruthenium (II) complexes with dipyridophenazine ligands.

Three symmetric ligands 7-methyl dipyrido-[3,2-a;2',3'-c]phenazine (dppz-CH(3)), 7-nitro dipyrido-[3,2-a;2',3'-c]phenazine (dppz-NO(2)) and benzo[i]dipyrido-[3,2-a;2',3'-c]phenazine (dppn) and their ruthenium(II) complexes [Ru(en)(2)(L)][ClO(4)](2) (en= ethylenediamine), L= dppz-CH(3), dppz-NO(2) and dppn have been synthesized and characterized by IR, (1)H, (13)C NMR and Mass spectra. The interactions of these complexes with calf thymus DNA have been investigated by spectrophotometric, spectrofluorimetric, circular dichroism, viscosity and thermal denaturation studies. As the planar extension of the intercalative ligand increases, the interaction of the complex with DNA increases, indicating that the size and shape of the intercalalative ligand has a marked effect on the strength of interaction.