Correlation of conventional and liquid-based cytology and their meaning in management of precancerous cervical lesions.

Aim: Introduction of efficiency of liquid-based citoscreen cytology

Method: Conventional cytology with Papanicolaou method and comparison with novel cytology liquid-based method in women with histological findings associated to Human Papilloma Virus praecancerous lesions for "gold standard" method.

Results: 100 women with praecancerous cervical lesions were included in the study. In all of the women, biopsy and endocervical curettage were made, and histological results were taken as a "gold standard".

Operative treatment of cervical premalignant lesions and the presence of high-risk human papilloma virus as etiologic agent.

The conization as an excisional method is used as an operative treatment of high-risk premalignant cervical lesions. Early detection and removal may stop the developing process that leads to invasive carcinoma. The study presents a group of 100 women, operated with "cold knife" conization during the year 2002 at the 1st Operative Oncologic Department of the Gynecology and Obstetrician Clinic - Medical Faculty, Skopje.