Publications by authors named "J Nanda"
Self-assembly of amino acids and short-peptide derivatives attracted significant curiosity worldwide due to their unique self-assembly process and wide variety of applications. Amino acid is considered one of the important synthons in supramolecular chemistry. Self-assembly processes and applications of unfunctionalized native amino acids have been less reported in the literature.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the levels of non-structural protein 1 (NS1) and the NS1-Thrombin complex (NST) in relation to the severity of dengue, focusing on 86 patients with varying degrees of severity and associated health conditions.
- Results indicated that while NS1 has a significant impact on dengue outcomes, NST is a better biomarker for predicting disease progression, showing greater accuracy in distinguishing between different severity levels of dengue.
- The findings highlight NST's potential role in enhancing understanding of dengue severity and its usefulness as a biomarker during acute dengue presentations.
Article Synopsis
- - Phenotypic plasticity in cancer, particularly prostate cancer (PCa), leads to resistance against androgen receptor-targeted therapies, highlighting the need to understand its driving mechanisms to prevent resistance emergence.
- - The study found that loss of the tristetraprolin (TTP) gene (ZFP36) increases NF-κB activation, correlating with more aggressive disease and recurrence, especially when PTEN, another key driver in PCa, is also lost.
- - Targeting the NF-κB pathway with an inhibitor (DMAPT) showed promising therapeutic effects in tumors exhibiting co-loss of ZFP36 and PTEN, suggesting a potential new treatment strategy for castration-resistant PCa.
Sulfide solid-state electrolytes (SSEs) in all-solid-state batteries (SSBs) are recognized for their high ionic conductivity and inherent safety. The LiNiMnCoO (NMC811) cathode offers a high thermodynamic potential of approximately 3.8 V Li/Li and a theoretical specific capacity of 200 mA h g.
View Article and Find Full Text PDF