Dysregulation of Myelination in Focal Cortical Dysplasia Type II of the Human Frontal Lobe.

Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified into different subtypes including FCD IIa and IIb, characterized by a blurred gray-white matter boundary or a transmantle sign indicating abnormal white matter myelination. Recently, we have shown that myelination is also compromised in the gray matter of FCD IIa of the temporal lobe.

Platelet rich fibrin three-layer reconstruction of the sellar floor after endoscopic endonasal transsphenoidal approach: technical note and initial experience.

Background: Cerebrospinal fluid (CSF) leakage frequently complicates endoscopic endonasal transsphenoidal pituitary resections, despite the use of lumbar drains, nasoseptal flaps, or commercial dura sealants. Managing this complication often requires revision surgery and increases the risk of infection. Platelet-rich fibrin (PRF), an affordable autologous biomaterial derived from the patient's blood through short, angulated centrifugation, contains growth factors and leukocytes embedded in a fibrin matrix.

Factors affecting gasless reduced-port laparoscopic myomectomy (GRP-LM) using a subcutaneous abdominal wall lifting method: a retrospective analysis of a large cohort of 966 cases in Japan.

Objective: To evaluate the usefulness of gasless reduced-port laparoscopic myomectomy (GRP-LM) using a subcutaneous abdominal wall lifting method.

Methods: In GRP-LM, after lifting the abdominal wall by a subcutaneous abdominal wall lifting method, a 1.5-cm incision is made in the lateral abdomen, Lap Protector is placed.

Preparation of Antifog Hard Coatings Based on Carboxy-Functionalized Polyhedral Oligomeric Silsesquioxane Cross-Linked with Oligo(ethylene glycol)s.

In this study, we prepared antifog hard coatings by heating a mixture of carboxy-functionalized polyhedral oligomeric silsesquioxane (POSS-C) and oligo(ethylene glycol)s (OEGs, HO(CHCHO) H, = 1-6) in ,-dimethylformamide, applying the mixture onto a glass substrate, and subsequently removing the solvent via heating. In addition, we evaluated the water resistance, hardness, and antifogging performance of the coatings. In particular, the coating produced at a 2:1 functional group ratio of POSS-C to tetraethylene glycol (OEG, = 4) coating exhibited high surface hardness (6H), as determined using pencil scratch testing.