Publications by authors named "J Nachega"
Hidden in plain sight: the threat of mpox to children and adolescents.
Lancet Child Adolesc Health
December 2024
On August 14, 2024, following a regional declaration by the Africa Centres for Disease Control and Prevention, the World Health Organization declared mpox a Public Health Emergency of International Concern, marking the second such declaration in two years. A series of outbreaks involving the more virulent clade I virus (compared to clade II, which caused a global outbreak in 2022), has now spread in 13 African countries, exposing the inadequacies of the public health infrastructure in these settings. There was significant investment during the 2022 global outbreak, but these efforts failed to address vaccine access and treatment in the Global South.
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- Enhancing clinical trial skills in Africa is crucial for improving the continent’s ability to prevent, prepare for, and respond to pandemics.
- The text highlights the major challenges faced in conducting clinical trials in Africa and shares insights from the CONCVACT project, which focused on COVID-19 vaccine trials.
- Key takeaways include the need for regional cooperation, building local capacities, and creating standardized procedures for clinical trials.
Article Synopsis
- The emergence of Clade Ib monkeypox virus (MPXV), known for sustained human-to-human transmission, has raised public health concerns as it spreads beyond endemic regions, first identified in South Kivu province.
- Recent cases of Clade Ib in North Kivu province highlight the need for public health efforts to address non-sexual transmission, especially involving children under 15, and to adapt community messaging accordingly.