Publications by authors named "J NOSEK"

Article Synopsis
  • Respiration in eukaryotes relies on mitochondrial protein synthesis, which is guided by organelle-specific ribosomes that translate mitochondrial mRNAs, although many details of this process remain unclear.
  • Researchers mapped the 3' ends of mitochondrial mRNAs in different yeast species and identified sequence elements called 3'-end RNA processing elements (3'-RPEs), essential for processing mitochondrial RNA.
  • The study highlights the role of the Rmd9 protein in this processing, showing its interaction with 3'-RPEs across various yeast species, and uncovers a unique translation mechanism involving removed stop codons in certain mRNAs.
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Handwashing is a vital skill for maintaining health and hygiene. For individuals with intellectual and developmental disabilities (IDD), such as autism spectrum disorder, evidence-based strategies, such as prompting and task analysis, may be effective in teaching these skills. Due to the shortage of experts who teach individuals with IDD skills such as handwashing, staff working with children need a means of ensuring these instructional strategies are implemented with fidelity.

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Article Synopsis
  • Ribosomes are essential ribonucleoprotein complexes present in all life forms, with size variations in ribosomal RNAs (rRNAs) due to specific regions called expansion segments (ESs).
  • The study focuses on yeasts from the Magnusiomyces/Saprochaete clade, revealing they lack significant portions of rRNAs compared to typical ones found in Saccharomyces cerevisiae, particularly in the expansion segments.
  • Despite the reduced size of rRNAs, the overall composition of ribosomal proteins remains largely unchanged, and similar reductions in rRNA size are observed across other lineages in the Saccharomycotina subphylum.
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We report the genome sequence of the pathogenic yeast strain SR23 (CBS 7157) used in a number of experimental studies. The nuclear genome assembly consists of eight chromosome-sized contigs with a total size of 13.04 Mbp (N50 2.

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