Short-Term Effectiveness and Tolerability of Vigabatrin Therapy in Infantile Epileptic Spasms Syndrome.

The study evaluated the short-term effectiveness and tolerability of vigabatrin therapy in children with infantile epileptic spasms syndrome (IESS). Children with IESS were enrolled within two weeks of initiation of vigabatrin and prospectively followed up to 12 wk for complete cessation of epileptic spasms (ES) and occurrence of adverse events. Of 107 children studied, there was a preponderance of structural etiology (82.

Synthetic MRI derived relaxometry parameters: a new insight into characterization of ring enhancing lesions of brain.

Background And Purpose: Synthetic MRI utilizes the quantitative relaxometry parameters to generate multiple contrast images through a single acquisition. We tried to explore the utility of synthetic MRI derived relaxometry parameters in evaluation of ring enhancing lesions of brain.

Materials And Methods: This was a prospective study.

All-fiber E + S band continuously tunable bismuth-doped germanosilicate fiber laser.

In this Letter, we present an all-fiber bismuth (Bi)-doped germanosilicate fiber laser that is continuously tunable within the range of 1425-1475 nm, enabled by a tunable optical filter. A maximum output power of 86.4 mW was achieved at 1450 nm with a slope efficiency of 13.

Significance of the Sparing Pronator Quadratus for Volar Plating of Distal Radius Fractures: A Prospective Study.

Background Pronator quadratus (PQ) acts as the pronator of the wrist and stabiliser of the distal radioulnar joint; it also provides a protective cover over the edge of the plate, preventing friction and subsequent rupture of flexor tendons. The repair of PQ is often difficult, and its durability is questionable; hence, preserving the PQ while volar plating distal radius fractures is advocated. Methods In this prospective randomised trial, 60 patients with a fracture of the distal end of the radius of AO-type (Arbeitsgemeinschaft für Osteosynthesefragen) 23 A2, A3, B1, B3, C1, and C2 were treated with volar plate fixation using either the PQ-releasing and repair approach (Group A, n = 30) or the PQ-sparing approach (Group B, n = 30), allowed by simple randomisation.

Integration of a surgical bipolar ablation device within an electroanatomical mapping system during epicardial ventricular tachycardia ablation via video-assisted thoracoscopic surgery: a case report.

Background: Epicardial ventricular tachycardia (VT) ablation is an established approach in patients with epicardial arrhythmogenic foci and is most commonly performed via percutaneous access. An alternative approach is via video-assisted thoracoscopic surgery (VATS), although reports of this technique are limited to the use of catheter-based technologies for radiofrequency ablation delivery.

Case Summary: A 55-year-old man with non-ischaemic cardiomyopathy presented with recurrent VT despite medical therapy.