Publications by authors named "J N Quintero-Zarate"
Article Synopsis
- A previous study identified OXA-1 and inhibitor-resistant TEM β-lactamases as major mechanisms of amoxicillin-clavulanate resistance in E. coli in Spain.
- The current research analyzed the genetic and virulence characteristics of clinical AMC-resistant E. coli strains compared to AMC-susceptible strains, revealing different prevalent clones for each resistance group.
- Results indicated that AMC-susceptible E. coli had a more diverse population structure and higher virulence factor presence compared to OXA-1 and IRT producers.
Seven Enterobacter cloacae isolates and seven Klebsiella pneumoniae isolates harbouring a phenotype compatible with the production of a metallo-β-lactamase were recovered between 2009 and 2011 in three Intensive Care Units of Hospital Vall d'Hebron (Barcelona, Spain). The presence of bla(VIM), bla(IMP), bla(NDM), bla(CTX-M), aac(6')-Ib, qnrA, qnrB and qnrS genes was screened by polymerase chain reaction (PCR) and sequencing. Clonal relatedness of the isolates was assessed by pulsed-field gel electrophoresis (PFGE) and, in the case of K.
View Article and Find Full Text PDFObjectives: The present study was carried out to evaluate the current prevalence of the clonal group O25b:H4-B2-ST131 among extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (ESBLEC) collected in the Hospital Vall d'Hebron in Barcelona (Spain) with regard to other clonal groups and to characterize their genetic background.
Methods: Ninety-four consecutive non-duplicate ESBLEC isolates collected from May to December 2008 were studied. ESBL enzymes, phylogenetic groups, serotypes, virulence genes, sequence types (STs) and PFGE profiles were determined.