p16(INK4a)/Ki-67 dual stain cytology for cervical cancer screening in Thika district, Kenya.

Background: The identification of suited early detection tests is one among the multiple requirements to reduce cervical cancer incidence in developing countries.

Methods: We evaluated p16(INK4a)/Ki-67 dual-stain cytology in a screening population in Thika district, Kenya and compared it to high-risk human papillomavirus (HR-HPV) DNA testing and visual inspection by acetic acid (VIA) and Lugol's iodine (VILI).

Results: Valid results for all tests could be obtained in 477 women.

Factors affecting uptake of cervical cancer early detection measures among women in Thika, Kenya.

In this study, 50 in-depth interviews were carried out with women from the general population in Thika, Kenya. We explored awareness, attitudes, and behavior toward cervical cancer and screening measures among the women. The concept of the health belief model (HBM) was used to develop the topics for the in-depth interviews.

Molecular characterization of HIV type 1 among HIV-infected respondents in a cohort being prepared for HIV Phase III vaccine clinical trials, Western Kenya.

Kenya is one of the sub-Saharan African countries affected by HIV-1 infection and AIDS. We investigated HIV-1 genetic diversity in 130 individuals from Busia, Bungoma, and Kakamega in western Kenya as part of an HIV-1 vaccine feasibility study in preparation for Phase III efficacy clinical trials. After RNA extraction the partial gag (484 bp) and env (1297 bp) regions were amplified and directly sequenced.

Pathogenic Escherichia coli and food handlers in luxury hotels in Nairobi, Kenya.

Background: The epidemiology and virulence properties of pathogenic Escherichia coli among food handlers in tourist destination hotels in Kenya are largely uncharacterized.

Method: This cross-sectional study among consenting 885 food handlers working in nine luxurious tourist hotels in Nairobi, Kenya determined the epidemiology, virulence properties, antibiotics susceptibility profiles and conjugation abilities of pathogenic Escherichia coli.

Result: Pathogenic Escherichia coli was detected among 39 (4.

Health status and health seeking behaviour of the elderly persons in Dagoretti division, Nairobi.

Objective: To determine the health status and the health seeking behaviour of the elderly people aged 65 years and above.

Design: A descriptive cross sectional study of individuals interviewed through questionnaires and focus groups discussions.

Setting: Dagoretti Division, Nairobi Province, Kenya.