Publications by authors named "J N Lopez-Canoa"
Aims: This study aims to investigate the clinical and biochemical characteristics of patients with atrial fibrillation (AF) referred for ablation who develop arrhythmia-induced cardiomyopathy (AiCM) as well as their long-term outcomes after catheter ablation (CA).
Methods And Results: A prospective multicentre study was conducted on consecutive AF patients who underwent CA. AiCM was defined as the development of heart failure in the presence of AF and an improvement of left ventricular fraction by at least 10% at 6 months after ablation.
Pheochromocytoma is a rare cause of ischaemic heart disease. We present the case of a patient in whom pheochromocytoma was diagnosed following ischaemic heart disease with absence of coronary lesions, demonstrating the importance of taking it into account in the differential diagnosis in these cases, especially considering that curative treatment is available.
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- The study investigates whether biomarkers associated with fibrosis and adiposity can effectively predict low-voltage areas (LVA) in the heart and the likelihood of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI).
- A total of 299 patients were analyzed, revealing that age, left atrium size, and a new combined score based on AF type and FABP4 levels are significant predictors for both LVA and AF recurrence.
- The findings suggest that incorporating adiposity markers like FABP4 into traditional classifications of atrial cardiomyopathy enhances prediction accuracy for both LVA presence and AF recurrence, while galectin-3 (Gal-3) did not show additional predictive benefits.
Inflammation is one of the mechanisms involved in heart failure (HF) pathophysiology. Thus, the acute phase reactant protein, orosomucoid, was associated with a worse post-discharge prognosis in acute HF (AHF). However, the presence of anti-inflammatory adipokine, omentin, might protect and reduce the severity of the disease.
View Article and Find Full Text PDFAims: Adiposity plays a key role in the pathogenesis of atrial fibrillation (AF). Our aim was to study the sex differences in adipokines levels according to AF burden.
Methods And Results: Two independent cohorts of patients were studied: (i) consecutive patients with AF undergoing catheter ablation (n = 217) and (ii) a control group (n = 105).