Anatomical Considerations for Injectable Fillers in the Face: How to Reduce Complications and Optimize Aesthetic Results.

The popularity of minimally invasive injectable aesthetic treatments has grown exponentially with over thirteen million neurotoxin and dermal filler injections being performed in 2014. While aesthetic results can be dramatic and convalescence minimal, significant complications including vascular compromise, neuropraxia, and blindness have been reported. Thorough knowledge of the complex anatomy in this area and the use of anatomic landmarks can help the physician obtain improved aesthetic results by deploying fillers in the appropriate anatomic plane and avoiding inadvertent injury to important neurovascular structures in this area.

Efficacy and Tolerability of a Procedure Enhancement System with TriHex Technologyas a Pre- and Post-Radiofrequency Microneedling Regimen.

Postoperative recovery is an important consideration for patients planning dermal rejuvenation procedures. A topical procedure enhancement system (PES) containing a tripeptide and hexapeptide (TriHex Technology; Alastin Skincare, Carlsbad, CA) hastens recovery from facial rejuvenation procedures, such as laser resurfacing. We assessed the efficacy and tolerability of the PES compared to a standard-of-care antioxidant regimen for improving recovery following three monthly facial radiofrequency (RF) microneedling treatments.

Bayesian inversion of a diffusion model with application to biology.

A common task in experimental sciences is to fit mathematical models to real-world measurements to improve understanding of natural phenomenon (reverse-engineering or inverse modelling). When complex dynamical systems are considered, such as partial differential equations, this task may become challenging or ill-posed. In this work, a linear parabolic equation is considered as a model for protein transcription from MRNA.

Network inference from population-level observation of epidemics.

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e., the number of infected individuals at a finite set of discrete times of a single realisation of the epidemic), the only information likely to be available in real world settings.

Split-Sided Chest Study of Skin Rejuvenation Comparing Low-Energy, 1,927-nm Thulium Fractional Laser Treatment Prior to Photodynamic Therapy Versus Photodynamic Therapy Alone.

Background And Objectives: Treatment of photoaging and intrinsic aging of the chest, with the associated concerns of skin roughness, uneven pigmentation, laxity, atrophy, and telangiectasias, can be problematic because of the potential for worsened esthetic outcomes with existing treatments. This study assessed the efficacy and safety of using nonablative fractional laser therapy (FLT) pretreatment with photodynamic therapy (PDT) versus PDT alone for chest rejuvenation.

Study Design/materials And Methods: In a randomized, evaluator-blinded, split-sided study, adult female patients with photodamage to the chest received three treatment courses over an 8-week period with follow-up visits at Weeks 12 and 20.