Objective: To assess the cost-effectiveness of modifying current antenatal screening by adding first trimester structural anomaly screening to standard of care second trimester anomaly screening.
Design: Health economic decision model.
Setting: National Health Service (NHS) in England and Wales.
Concrete has been widely utilized as a radiation shielding material due to its properties and structural integrity. This study aims to evaluate the efficiency of ordinary concrete versus barite concrete as radiation shielding materials, focusing on the physical aspects and changes in crystal size lattice parameters after neutron irradiation. Specifically, the research investigates the shielding effectiveness of these materials across different grades (M15, M25, M35, and M45) against gamma-ray sources Cobalt-60 and Caesium-137.
View Article and Find Full Text PDFThree amylin receptors (AMYRs) mediate the metabolic actions of the peptide hormone amylin and are drug targets for diabetes and obesity. AMYR, AMYR, and AMYR are heterodimers consisting of the G protein-coupled calcitonin receptor (CTR) paired with a RAMP1, -2, or -3 accessory subunit, respectively, which increases amylin potency. Little is known about AMYR subunit interactions and their role in signaling.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
June 2024
This case report presents a 64-year-old male diagnosed with sinonasal primary squamous cell carcinoma (SNSCC), a rare and aggressive upper aerodigestive tract malignancy. Initially, he presented with unilateral recurrent epistaxis. Imaging and histopathology confirmed the diagnosis.
View Article and Find Full Text PDFBackground: The increased pervasiveness of digital health technology is producing large amounts of person-generated health data (PGHD). These data can empower people to monitor their health to promote prevention and management of disease. Women make up one of the largest groups of consumers of digital self-tracking technology.
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