Publications by authors named "J N Hugues"
Article Synopsis
- The study aimed to compare clinical outcomes of embryo transfers using euploid blastocysts based on their timing (D5 vs. D6) and quality.
- Results showed that D5 embryos had a significantly higher live birth rate (55.04%) compared to D6 embryos (38.71%), with embryo quality being a key factor in these outcomes.
- The findings suggest that selecting excellent quality D5 embryos leads to better IVF success rates, impacting decisions made by IVF teams and patients.
Subtle perturbations of ovarian steroidogenesis in patients classified as Poseidon Group 3. Which consequences for therapeutic strategy?
Front Endocrinol (Lausanne)
February 2024
The optimal strategy for stimulation of young women with a low ovarian reserve is still a challenging issue because the physio-pathogeny of this disorder is often unknown. As androgen production by the ovary plays a crucial role in folliculogenesis, it was tempting to speculate that subtle perturbations in ovarian steroidogenesis might participate to the low responsiveness to gonadotrophins. Indeed, analysis of human luteinized granulosa cells has recently provided evidence for some enzymatic deficits in steroidogenesis and altered response to gonadotrophins.
View Article and Find Full Text PDFPurpose: To evaluate the effectiveness of the progestin-primed ovarian stimulation (PPOS) protocol versus the gonadotropin-releasing hormone antagonist (GnRH-ant) protocol in ovarian stimulation.
Methods: In this retrospective cohort study, we included 804 patients who were treated between January 1, 2022, and July 1, 2023. Outcomes of ovarian stimulation were compared between the PPOS (n = 206) and GnRH-ant (n = 598).
Objectives: To evaluate the relationship between time since contraceptive implant placement and retrieval outcomes in patients with implant migration into the pulmonary artery.
Study Design: We reviewed all cases of pulmonary artery implant migration referred to the Marie Lannelongue hospital from 2015 through 2020. Using our hospital database, we collected patients' clinical data and removal information to assess the success of therapeutic management according to the delay between implant insertion and removal.