[Emergence of antifungal resistance: A creeping environmental threat?].

Antifungal resistance in humans is a clinical reality of increasing incidence that raises problems for patient care. In this current event, we discuss the link that can be made between the presence of antifungals in the environment and the development of resistance in humans, as well as the ecotoxicology of antifungals. The presence of antifungals in the environment has a health, but also an ecological impact.

Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1.

Alternative transcription start site (TSS) usage regulation has been identified as a major means of gene expression regulation in metazoans. However, in fungi, its impact remains elusive as its study has thus far been restricted to model yeasts. Here, we first re-analyzed TSS-seq data to define genuine TSS clusters in 2 species of pathogenic Cryptococcus.

[Role of the occupational medicine in the prevention of diseases and accidents].

Occupational medicine is an essential branch of preventive medicine that aims to protect the health of workers in the workplace. Any work situation exposes the worker to occupational hazards. The three levels of prevention applied in occupational medicine make it possible, together, to control risks.

CRAFT: Concept Recursive Activation FacTorization for Explainability.

Attribution methods, which employ heatmaps to identify the most influential regions of an image that impact model decisions, have gained widespread popularity as a type of explainability method. However, recent research has exposed the limited practical value of these methods, attributed in part to their narrow focus on the most prominent regions of an image - revealing "where" the model looks, but failing to elucidate "what" the model sees in those areas. In this work, we try to fill in this gap with CRAFT - a novel approach to identify both "what" and "where" by generating concept-based explanations.