Measuring social vulnerability in communities and its association with leprosy burden through spatial intelligence in central West Brazil to guide strategic actions.

Background: It is known that leprosy is a socially determined disease, but most studies using spatial analysis have not considered the vulnerabilities present in these territories.

Objectives: To measure the association between social vulnerability and the burden of leprosy in the urban space of Cuiabá.

Methods: Ecological study, carried out in Cuiabá, Brazil.

Potential of quartzite and Hevea brasiliensis wood in the production of cement-wood panels.

The incorporation of residues in cement matrices is a viable alternative for obtaining new products for civil construction and a sustainable solution for the disposal of materials discarded by industries. In this context, the objective of the study was to evaluate the potential use of quartzite and particles of Hevea brasiliensis in the production of cement-wood panels. Quartzite residues and Hevea brasiliensis wood particles were obtained and characterized.

Resting ECG findings in male Brazilian soccer players of different ethnicities: Results from the B-Pro Foot ECG study.

Objectives: To compare the prevalence of training-related ECG findings in white, mixed-race, and black male Brazilian soccer players.

Design: Multicenter observational study.

Methods: This study involved athletes aged 15 to 35 years from 82 professional clubs across Brazil's five regions.

Soluble CTLA-4 - A confounding factor in CTLA-4 based checkpoint immunotherapy in cancer.

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) is a receptor that inhibits the activity of T cells. The CTLA-4 gene consists of four different exons that enable four different isoforms of CTLA-4 to be generated through alternative splicing. Although sCTLA-4 might impede the therapeutic effect of anti-CTLA-4 treatments, the role of sCTLA-4 in the tumor microenvironment (TME) is not well understood.