Publications by authors named "J Murillo Diez"
A multi-task framework for breast cancer segmentation and classification in ultrasound imaging.
Comput Methods Programs Biomed
December 2024
Background: Ultrasound (US) is a medical imaging modality that plays a crucial role in the early detection of breast cancer. The emergence of numerous deep learning systems has offered promising avenues for the segmentation and classification of breast cancer tumors in US images. However, challenges such as the absence of data standardization, the exclusion of non-tumor images during training, and the narrow view of single-task methodologies have hindered the practical applicability of these systems, often resulting in biased outcomes.
View Article and Find Full Text PDFBackground And Objective: Currently, the management for pituitary apoplexy (PA) has been promoted toward a more conservative approach, particularly for patients with low-grade PA scores. Our aim was to investigate trends in PA management and compare clinical presentation, therapeutic approaches, and outcomes before and after 2017, additionally to evaluate long-term outcomes in conservatively treated patients.
Methods: Spanish multicenter, retrospective study.
GLP-1 Receptor Agonists Models for Type 1 Diabetes: A Narrative Review.
J Diabetes Sci Technol
October 2024
Background: Glucagon-like peptide 1 (GLP-1) is a hormone that promotes insulin secretion, delays gastric emptying, and inhibits glucagon secretion. The GLP-1 receptor agonists have been developed as adjunctive therapies for type 2 diabetes to improve glucose control. Recently, there has been an interest in introducing GLP-1 receptor agonists as adjunctive therapies in type 1 diabetes alongside automatic insulin delivery systems.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to identify patients with chronic hypoparathyroidism who either had adequate (AC) or not adequately controlled (NAC) disease, as poor control is linked to complications and increased mortality.
- Researchers analyzed data from 337 patients across 16 Spanish hospitals to assess disease control through biochemical criteria and clinical wellness, finding that many patients were not adequately controlled.
- Findings revealed that 45.9% to 63.1% of patients met the NAC criteria, with those who had dyslipidemia being at a greater risk, and NAC patients exhibited higher rates of associated comorbidities like chronic kidney disease and eye disorders compared to AC patients.
Integration of big data analytics in the investigation of the relationship between acromegaly and cancer.
Endocrinol Diabetes Nutr (Engl Ed)
October 2024
Article Synopsis
- The study aimed to assess the link between acromegaly and various types of cancer using big data and natural language processing techniques from electronic health records.
- Out of over 708,000 patients, 544 were diagnosed with acromegaly, showing a notably higher cancer incidence (7.7%) compared to those without the condition (3.9%).
- Acromegalic men were found to have a significantly higher prevalence of several cancers, particularly colorectal, bladder, and lymphoma, while acromegalic women showed a higher occurrence of thyroid cancer.