Publications by authors named "J Mukhopadhyay"
Article Synopsis
- Researchers are investigating (NHC) → S coordination interactions in chemical species like carbones and nitreones, with a focus on their rare but significant properties.
- The electron deficiency at the sulfur center leads to electron donation from the NHC unit, which increases with oxidation of sulfur, suggesting stronger interactions in oxidized systems.
- A study synthesized various (NHC) → SR complexes and their oxidized counterparts, confirming that the coordination interactions strengthen as oxygen atoms are added to the sulfur center.
The redox reaction of oxygen (OER & ORR) forms the rate determining step of important processes like cellular respiration and water splitting. Being a spin relaxed process governed by quantum spin exchange interaction, QSEI (the ground triplet state in O is associated with singlet oxygen in HO/OH), its kinetics is sluggish and requires inclusion of selective catalyst. Functionality and sustainability of solid oxide cell involving fuel cell (FC) and electrolyzer cell (EC) are also controlled by ORR (oxygen redox reaction) and OER (oxygen evolution reaction).
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- During the maintenance treatment phase for acute lymphoblastic leukemia (ALL), personalized dosing of oral antimetabolite drugs is essential, but challenging, leading to a higher relapse risk if not done correctly.
- An open-source R-based analytical toolkit, including the allMT R package and the VIATAMIN application, has been developed to assist in evaluating and improving drug titration during treatment.
- The toolkit provides visual analyses of drug dosing patterns, assesses prescriber compliance, and intends to integrate into a clinical support system for real-time adjustments, with future updates planned to include more factors affecting drug titration.
Group I and II introns are large catalytic RNAs (ribozymes) that are frequently encountered in fungal mitochondrial genomes. The discovery of respiratory mutants linked to intron splicing defects demonstrated that for the efficient removal of organellar introns there appears to be a requirement of protein splicing factors. These splicing factors can be intron-encoded proteins with maturase activities that usually promote the splicing of the introns that encode them (-acting) and/or nuclear-encoded factors that can promote the splicing of a range of different introns (-acting).
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- - The study explores new coordination interactions between N-heterocyclic carbenes (NHCs) and sulfur (S), expanding on previously known interactions with other main group elements like B, C, N, Si, and P.
- - Using quantum chemical analysis, the research found that the (NHC)→S interaction behaves as a coordination interaction, which is a different type of bonding compared to covalent bonds.
- - The synthesis involved creating divalent sulfur compounds with benzothiazole groups, and the process changed the electronic character of the bonds, confirmed by variations in C NMR spectra before and after methylation.