Mesenchymal stem cells - a promising perspective in the orofacial cleft surgery.

Autologous bone grafts provide the golden standard for closure of oronasal fistulas in the cleft palate. Augmentation may be performed also by homografts and various xenogenic or alloplastic materials to prevent morbidity at the donor site but they may cause many problems (transmission of infections, immune response etc.).

Vertical distraction osteogenesis of frontal segment and platelet-rich plasma in the edentulous mandible.

In patients with atrophy of the alveolar ridge of classes V and VI according to Cawood and Howell, the distraction osteogenesis (DO) is the only possibility of reconstruction connected with subsequent dental implants. This method was introduced by Ilizarov (1989), a Russian doctor. In the past few years, the distraction devices have undergone several changes and technical improvements.

Sjögren´s syndrome in present.

Sjögren´s syndrome is a systemic autoimmune disease characterized by a reduced function of exocrine glands, mainly salivary and lacrimal glands based on chronic plasmocellular infiltration. Syndrome includes affection of glands in gastrointestinal system, respiratory apparatus, skin, and vaginal mucosa. I tis described separately as a primary Sjögren´s syndrome or together with other inflammatory rheumatic diseases as a secondary Sjögren´s syndrome.

Use of thrombocyte concentrates in treatment of bone defects.

The use of plasma enriched with thrombocytes is a trend in surgical treatment of bone defects (Platelet-rich plasma, thrombocyte concentrate, hereinafter PRP). It contains a set of identified as well as unknown growth factors. It is nontoxic, has no immunity reaction, accelerates and improves the healing of wounds.

Squamous cell carcinoma and piercing of the tongue - a case report.

Tongue piercings can be associated with local and systemic complications. Local complications occur frequently immediately after the surgery but also long-term local effects can cause problems such as speech and swallowing difficulties. Aspiration, transmission of infectious diseases, hypersensitivity reaction belong to the systemic complications.