Extracellular matrix thermostability of breast gland carcinoma.

Thermostability of epithelial cell matrix in composition of normal and breast ductal carcinoma tissues at various stages of the disease has been studied in the temperature range 40-90°C with help of differential scanning calorimeter (DSC). It has been shown that the denaturation process has three stages of transition in both cases. The temperatures corresponding to maxima of these structural transitions (Td) in case of normal and ductal carcinoma tissues equals to 55 , 66,78 C and 48, 55, 60, 85°C, respectively.