First report of a successful pediatric heart transplantation from donation after circulatory death with distant procurement using normothermic regional perfusion and cold storage.

Heart transplantation (HT) from donation after circulatory death (DCD) is a promising alternative to expand the heart donor pool. Cold storage can be used in a strategy to successfully retrieve and transplant DCD hearts after reconditioning using normothermic regional perfusion for distant procurement. Herein, we present the first report of a pediatric DCD heart reconditioned with normothermic regional perfusion, preserved using only cold storage while being transported to a neighboring center, and then successfully transplanted after nearly 2 hours of cold static storage.

Successful clinical transplantation of hearts donated after circulatory death using normothermic regional perfusion.

Background: Heart transplantation (HT) from donation after circulatory death (DCD) has yet to achieve wide clinical application despite the encouraging resultsreported recently. In this study we describe 2 cases of successful adult DCD HT performed at our institution using an original protocol.

Methods: Our local abdominal DCD protocol was updated to allow DCD heart procurement, and was accepted by the institutional ethics committee.

A more than 20% increase in deceased-donor organ procurement and transplantation activity after the use of donation after circulatory death.

Background: Organ procurement and transplant activity from controlled donation after circulatory death (DCD) was evaluated over an 11-year period to determine whether this program influenced the transplant and donation after brain death (DBD) activities.

Material And Methods: Deceased donor (DD) procurement and transplant data were prospectively collected in a local database for retrospective review.

Results: There was an increasing trend in the potential and actual DCD numbers over time.

Delayed graft function does not harm the future of donation-after-cardiac death in kidney transplantation.

Introduction: Delayed graft function (DGF) occurs more frequently in kidney transplants from donation after cardiac death (DCD) than from donation after brain death (DBD). We investigated the effect of DGF on posttransplantation outcomes among grafts from controlled DCD kidneys.

Patients And Methods: This single-center retrospective study recruited 80 controlled DCD kidneys transplanted from January 2005 to December 2011.

Results of kidney transplantation from controlled donors after cardio-circulatory death: a single center experience.

The aim of this study was to determine results of kidney transplantation (KT) from controlled donation after cardio-circulatory death (DCD). Primary end-points were graft and patient survival, and post-transplant complications. The influence of delayed graft function (DGF) on graft survival and DGF risk factors were analyzed as secondary end-points.